canprot: Chemical Metrics of Differentially Expressed Proteins
Chemical metrics of differentially expressed proteins in cancer
and cell culture proteomics experiments. Data files in the package have amino
acid compositions of proteins obtained from UniProt and >250 published lists of
up- and down-regulated proteins in different cancer types and laboratory
experiments. Functions are provided to calculate chemical metrics including
protein length, grand average of hydropathicity (GRAVY), isoelectric point
(pI), carbon oxidation state, and stoichiometric hydration state; the latter
two are described in Dick et al. (2020) <doi:10.5194/bg-17-6145-2020>. The
vignettes visualize differences of chemical metrics between up- and
down-regulated proteins and list literature references for all datasets.
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