Individual Dose Optimization using Population Pharmacokinetics

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Documentation for package ‘posologyr’ version 1.2.4

• DESCRIPTION file.
• User guides, package vignettes and other documentation.
• Package NEWS.

Help Pages

error_model_comb1	Residual error model combined 1
error_model_comb2	Residual error model combined 2
error_model_mixednm	Residual error model mixed (idem NONMEM)
poso_dose_auc	Estimate the optimal dose for a selected target area under the time-concentration curve (AUC)
poso_dose_conc	Estimate the optimal dose for a selected target concentration
poso_estim_map	Estimate the Maximum A Posteriori individual parameters
poso_estim_mcmc	Estimate the posterior distribution of individual parameters by MCMC
poso_estim_sir	Estimate the posterior distribution of individual parameters by SIR
poso_inter_cmin	Estimate the optimal inter-dose interval for a given dose and a selected target trough concentration
poso_simu_pop	Estimate the prior distribution of population parameters
poso_time_cmin	Predict time to a selected trough concentration