Certara.NLME8: Utilities for Certara's Nonlinear Mixed-Effects Modeling Engine

Perform Nonlinear Mixed-Effects (NLME) Modeling using Certara's NLME-Engine. Access the same Maximum Likelihood engines used in the Phoenix platform, including algorithms for parametric methods, individual, and pooled data analysis. The Quasi-Random Parametric Expectation-Maximization Method (QRPEM) is also supported <https://www.page-meeting.org/default.asp?abstract=2338>. Execution is supported both locally or on remote machines. Remote execution includes support for Linux Sun Grid Engine (SGE), Simple Linux Utility for Resource Management (SLURM) grids, Linux and Windows multicore, and individual runs.

Version:	3.0.2
Depends:	R (≥ 4.0.0)
Imports:	xml2, batchtools (≥ 0.9.9), reshape, utils, data.table
Suggests:	testthat
Published:	2025-08-20
DOI:	10.32614/CRAN.package.Certara.NLME8
Author:	Soltanshahi Fred [aut], Michael Tomashevskiy [aut], James Craig [aut, cre], Shuhua Hu [ctb], Certara USA, Inc. [cph, fnd]
Maintainer:	James Craig <james.craig at certara.com>
License:	LGPL-3
NeedsCompilation:	no
Materials:	README
CRAN checks:	Certara.NLME8 results

Documentation:

Reference manual:

Certara.NLME8.html , Certara.NLME8.pdf

Downloads:

Package source:	Certara.NLME8_3.0.2.tar.gz
Windows binaries:	r-devel: Certara.NLME8_3.0.2.zip, r-release: Certara.NLME8_3.0.2.zip, r-oldrel: Certara.NLME8_3.0.2.zip
macOS binaries:	r-release (arm64): Certara.NLME8_3.0.2.tgz, r-oldrel (arm64): Certara.NLME8_3.0.1.tgz, r-release (x86_64): Certara.NLME8_3.0.2.tgz, r-oldrel (x86_64): Certara.NLME8_3.0.2.tgz
Old sources:	Certara.NLME8 archive

Reverse dependencies:

Reverse imports:

Certara.RsNLME, Certara.RsNLME.ModelExecutor

Linking:

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